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PROSPECTUS
SUPPLEMENT
(TO
PROSPECTUS DATED JUNE 11, 2010)
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Filed
pursuant to Rule 424(b)(3)
under
the Securities Act of 1933 in connection with
Registration
Statement No. 333-151654
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Common
Stock
This
Prospectus Supplement supplements and amends the prospectus dated June 11, 2010
relating to the offering of up to $150,000,000 in the aggregate of debt
securities, preferred stock, common stock, debt warrants, equity warrants and
any combination thereof. We are filing this prospectus supplement to reflect a
draw down by us pursuant to the Common Stock Purchase Agreement, dated June 11,
2010, between Kingsbridge Capital Limited (“Kingsbridge”) and ourselves.
This
prospectus supplement should be read in conjunction with the prospectus dated
June 11, 2010.
On
September 21, 2010, we delivered a notice to Kingsbridge to effect a draw down
of up to $2,087,667, consisting of a $587,667 minimum obligated amount and a
$1,500,000 supplemental amount. The first trading day of the
eight-day pricing period for this draw down was September 22,
2010. In connection with this draw down, we issued an aggregate of
5,272,361 shares of our common stock to Kingsbridge at an aggregate purchase
price of $972,657, resulting in net proceeds to us of $954,663 after deducting
fees due to Kingsbridge under the Stock Purchase Agreement. The
settlement dates for this draw down were September 28, 2010 and October 4,
2010.
Investing
in our common stock involves significant risks. See “Risk Factors”
beginning on Page 4 of the prospectus, as well as the section entitled “Risk
Factors” included in our recent quarterly and annual reports filed with the
Securities and Exchange Commission.
Neither
the Securities and Exchange Commission nor any state securities commission has
approved or disapproved of these securities or determined if this prospectus is
truthful or complete. Any representation to the contrary is a criminal
offense.
The date
of this prospectus supplement is October 5, 2010.