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PROSPECTUS
SUPPLEMENT
(TO
PROSPECTUS DATED JUNE 11, 2010)
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Filed
pursuant to Rule 424(b)(3)
under
the Securities Act of 1933 in connection with
Registration
Statement No. 333-151654
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Common
Stock
This
Prospectus Supplement supplements and amends the prospectus dated June 11, 2010
relating to the offering of up to $150,000,000 in the aggregate of debt
securities, preferred stock, common stock, debt warrants, equity warrants and
any combination thereof. We are filing this prospectus supplement to reflect a
draw down by us pursuant to the Common Stock Purchase Agreement, dated June 11,
2010, between Kingsbridge Capital Limited (“Kingsbridge”) and ourselves. This
prospectus supplement should be read in conjunction with the prospectus dated
June 11, 2010.
On
January 12, 2011, we delivered a notice to Kingsbridge to effect a draw down of
up to $2,021,700. The first trading day of the eight-day pricing
period for this draw down was January 13, 2011. In connection with
this draw down, we issued an aggregate of 314,179 shares of our common stock to
Kingsbridge at an aggregate purchase price of $991,275, resulting in net
proceeds to us of $972,937 after deducting fees due to Kingsbridge under the
Stock Purchase Agreement. The settlement dates for this draw down
were January 20, 2011 and January 26, 2011.
Investing
in our common stock involves significant risks. See “Risk Factors”
beginning on Page 4 of the prospectus, as well as the section entitled “Risk
Factors” included in our recent quarterly and annual reports filed with the
Securities and Exchange Commission.
Neither
the Securities and Exchange Commission nor any state securities commission has
approved or disapproved of these securities or determined if this prospectus is
truthful or complete. Any representation to the contrary is a criminal
offense.
The date
of this prospectus supplement is January 27, 2011.